产品货号：
Z22924
中文名称：
PALB2抗体
英文名称：
Anti-PALB2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PALB2 Antibody |
| 指标别名 | FANCN;PALB2;partner and localizer of BRCA2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | PALB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | PALB2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human PALB2.The immunogen is located within amino acids 940 - 990 of PALB2. |
| 计算分子量 | 131kDa |
| 成分 | PALB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | PALB2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The breast cancer early onset proteins BRCA1 and BRCA2 are central to the repair of DNA damage by homologous recombination and are strongly associated with inherited breast and ovarian cancer.The protein PALB2 is required for the localization of BRCA2 to sites of DNA damage and like BRCA1 and 2 is a breast cancer susceptibility gene.PALB2 is thought to function through directly binding to BRCA1,which allows the PALB2 protein to organize BRCA2 and the recombinase RAD51 at the site of DNA damage.Analysis of the BRCA1-PALB2-BRCA2-RAD51network may allow predictions to be made of the responsiveness of a particular tumor to therapeutic treatments. |
| Uniprot ID | Q86YC2 |
| 基因名全称 | Partner and localizer of BRCA2 |
| 蛋白名全称 | Partner and localizer of BRCA2 |
| 推荐稀释比 | PALB2 antibody can be used for detection of PALB2 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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